Enhancing the activity of biocatalysts supported on calcium phosphate by inducing mesoporosity with phosphopeptides

Preventing enzyme deactivation while increasing their accessibility by adsorption in mesopores remains a key challenge the design of biocompatible supported enzymatic catalysts. Herein, it is expected that food-grade monomeric or polymeric glycopeptides containing organic phosphate groups (as casein phosphopeptide derivatives) enhances entrapment over one pot method wet precipitation calcium (CaP) leading to hybrid organic/inorganic catalyst. The catalyst was prepared and phosphorous presence either glycopeptide glycopeptide. These had an influence on electrostatic stabilization during nucleation particles, as tracked dynamic light scattering scanning electron microscopy.The derivatives, were able decrease crystallization degree demonstrated XRD solid-state NMR analysis. Furthermore, according N2 sorption data, derivatives induced interparticle mesopores, which might be responsible enhanced activity biocatalyst improved from 52 (+/−19) NLU·g−1 without compound 607 (+/−34) NLU·g−1.